Dietary effects on Lp(a) levels.
نویسندگان
چکیده
Professor DahlCn’s blank statement that diet has a negligible effect on lipoprotein (a) (Lp(a)) levels [ 1] is correct for conventional lipid-lowering diets, which lower low density lipoprotein (LDL) and sometimes high density lipoprotein (HDL) levels, but hardly affect Lp(a). There is, however, an interesting exception in the form of dietary tram fatty acids, which are unsaturated fatty acids with one or more double bonds in the tram instead of the more usual cis configuration. Intakes in various populations range from l-10 g per day. Three studies in 2 laboratories have shown that tram fatty acids raise Lp(a) in man. Nestel et al. [2] fed 27 mildly hypercholesterolemic men diets enriched with 5%-7% of energy from palmitic acid, oleic acid or tram monounsaturated fatty acids for 3 weeks, and measured Lp(a) by radioimmunoassay. Mean Lp(a) levels (*SD) were 296 f 220 U/l on the
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ورودعنوان ژورنال:
- Atherosclerosis
دوره 113 1 شماره
صفحات -
تاریخ انتشار 1995